余韵，女，副研究员。
1998年7月获上海第二医科大学医学检验学士学位。2004-2009年攻读陈国强教授的在职硕博连读研究生，并获得博士学位。在过去十年中，先后从事氧化砷诱导白血病细胞凋亡的机制研究，并开展利用二维电泳和蛋白质芯片技术识别肿瘤标志物的研究工作，取得初步进展。期间，作为第一作者在《Oncology》发表的有关肿瘤标志物的研究论文在发表后3年内被他人引用达38次。2006年作为课题负责人承担国家自然科学青年基金《新喜树碱衍生物诱导白血病细胞凋亡的体内外研究》一项，期间围绕该课题应用蛋白质组学技术开展新型小分子化合物诱导AML细胞凋亡的信号分子网络调控机制研究，相关研究成果在《Journal of proteome research》发表。并在此基础上，就新发现的细胞凋亡信号相关分子进行深入的功能研究，这些原创性工作可能为研究细胞凋亡的分子机制提供新的线索。目前，以第一作者或并列第一作者发表论文3篇，参与发表论文13篇。

1.Yu Y, Wang LS, Shen SM, Xia L, Zhang L, Zhu YS, Chen GQ. Subcellular proteome analysis of camptothecin analog NSC606985-treated acute myeloid leukemic cells. J Proteome Res. 2007; 6(9):3808-18.
2.Yu Y, Chen S, Wang LS, Chen WL, Guo WJ, Yan H, Zhang WH, Peng CH, Zhang SD, Li HW, Chen GQ. Prediction of pancreatic cancer by serum biomarkers using surface-enhanced laser desorption/ionization-based decision tree classification. Oncology. 2005; 68(1):79-86
3.Song MG, Gao SM, Du KM, Xu M, Yu Y, Zhou YH, Wang Q, Chen Z, Zhu YS, Chen GQ. Nanomolar concentration of NSC606985, a camptothecin analog, induces leukemic-cell apoptosis through protein kinase Cdelta-dependent mechanisms. Blood. 2005; 105(9):3714-21.
4.Zhu Q, Zhang JW, Zhu HQ, Shen YL, Flexor M, Jia PM, Yu Y, Cai X, Waxman S, Lanotte M, Chen SJ, Chen Z, Tong JH. Synergic effects of arsenic trioxide and cAMP during acute promyelocytic leukemia cell maturation subtends a novel signaling cross-talk. Blood. 2002; 99(3):1014-22.
5.Jiang Y, Xue ZH, Shen WZ, Du KM, Yan H, Yu Y, Peng ZG, Song MG, Tong JH, Chen Z, Huang Y, Lubbert M, Chen GQ. Desferrioxamine induces leukemic cell differentiation potentially by hypoxia-inducible factor-1 alpha that augments transcriptional activity of CCAAT/enhancer-binding protein-alpha. Leukemia. 2005;19(7):1239-47.
6.Cai X, Yu Y（并列第一作者）, Huang Y, Zhang L, Jia PM, Zhao Q, Chen Z, Tong JH, Dai W, Chen GQ. Arsenic trioxide-induced mitotic arrest and apoptosis in acute promyelocytic leukemia cells. Leukemia. 2003;17(7):1333-37.
7.Yan H, Peng ZG, Wu YL, Jiang Y, Yu Y, Huang Y, Zhu YS, Zhao Q, Chen GQ. Hypoxia-simulating agents and selective stimulation of arsenic trioxide-induced growth arrest and cell differentiation in acute promyelocytic leukemic cells. Haematologica. 2005; 90(12):1607-16.
8.Cai X, Shen YL, Zhu Q, Jia PM, Yu Y, Zhou L, Huang Y, Zhang JW, Xiong SM, Chen SJ, Wang ZY, Chen Z, Chen GQ. Arsenic trioxide-induced apoptosis and differentiation are associated respectively with mitochondrial transmembrane potential collapse and retinoic acid signaling pathways in acute promyelocytic leukemia. Leukemia. 2000;14(2):262-70.
9.Yuan TT, Huang Y, Zhou CX, Yu Y, Wang LS, Zhuang HY, Chen GQ. Nuclear translocation of dihydrofolate reductase is not a pre-requisite for DNA damage induced apoptosis. Apoptosis. 2009;14(5):699-710.
10.Guo M, Song LP, Jiang Y, Liu W, Yu Y, Chen GQ. Hypoxia-mimetic agents desferrioxamine and cobalt chloride induce leukemic cell apoptosis through different hypoxia-inducible factor-1alpha independent mechanisms. Apoptosis. 2006 ;11(1):67-77
11.Zhang N, Zhang HW, Xia L, Zheng Y, Yu Y, Zhu YS, Chen GQ, Di W. NSC606985 induces apoptosis, exerts synergistic effects with cisplatin and inhibits hypoxia-stabilized HIF-1a protein in human ovarian cancer cells. Cancer Letters. 2009;278(2):139-144
12.Jin X, Wang LS, Xia L, Zheng Y, Meng C, Yu Y, Chen GQ, Fang NY. Hyper-phosphorylation of alpha-enolase in hypertrophied left ventricle of spontaneously hypertensive rat. Biochem Biophys Res Commun. 2008; 371(4):804-09.
13.Xue ZH, Jiang Y, Yu Y, Wang LS, Chen GQ, Zhao Q. Metavanadate suppresses desferrioxamine-induced leukemic cell differentiation with reduced hypoxia-inducible factor-1alpha protein. Biochem Biophys Res Commun. 2005; 332(4):1140-45.
15.Wang S, Zheng Y, Yu Y, Xia L, Chen GQ, Yang YZ, Wang LS. Phosphorylation of beta-actin by protein kinase C-delta in camptothecin analog-induced leukemic cell apoptosis. Acta Pharmacol Sin. 2008; 29(1):135-42.
16.Chen GQ, Wang LS, Wu YL, Yu Y. Leukemia, an effective model for chemical biology and target therapy. Acta Physiologica Sin. 2007;28 (9) :1316-1324.